CALB1 antibody (AA 7-96)

Catalog No. ABIN7876522

The Mouse Monoclonal anti-CALB1 antibody (Clone CALB1-3333) (ABIN7876522) specifically detects CALB1 in ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for CALB1 antibody (AA 7-96) (ABIN7876522)

Target: CALB1 (Calbindin (CALB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CALB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CALB1-3333

Product Details anti-CALB1 Antibody

Binding Specificity: AA 7-96

Purpose: CALB1 Antibody / Calbindin (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 7-96) was used as the immunogen for this CALB1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the CALB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CALB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CALB1

Target: CALB1 (Calbindin (CALB1))

Alternative Name: CALB1

Background: The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 and , Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin and Parvalbumin (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.

UniProt: P05937