Recombinant CALB1 antibody (AA 7-96)

Catalog No. ABIN7876526

This Mouse Monoclonal antibody specifically detects CALB1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant CALB1 antibody (AA 7-96) (ABIN7876526)

Target: CALB1 (Calbindin (CALB1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CALB1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RCALB1-8499

Product Details anti-CALB1 Antibody

Binding Specificity: AA 7-96

Purpose: CALB1 Antibody / Calbindin 1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 7-96) from the human protein was used as the immunogen for the CALB1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CALB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CALB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CALB1

Target: CALB1 (Calbindin (CALB1))

Alternative Name: CALB1

Background: The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 Alpha and Beta, Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin Alpha and Parvalbumin Beta (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.

UniProt: P05937