IMMT antibody (AA 700-729)

Catalog No. ABIN7876548

The Rabbit Polyclonal anti-IMMT antibody is suitable to detect IMMT in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for IMMT antibody (AA 700-729) (ABIN7876548)

Target: IMMT (Inner Membrane Protein, Mitochondrial (IMMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMMT antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IMMT Antibody

Binding Specificity: AA 700-729

Purpose: IMMT Antibody / MIC60

Purification: Purified

Immunogen: A portion of amino acids 700-729 from the human protein was used as the immunogen for the IMMT antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the IMMT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IMMT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IMMT

Target: IMMT (Inner Membrane Protein, Mitochondrial (IMMT))

Alternative Name: IMMT

Background: Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology.

UniProt: Q16891