TIMELESS antibody (AA 72-1050)

Catalog No. ABIN7876618

The Rabbit Polyclonal anti-TIMELESS antibody (ABIN7876618) specifically detects TIMELESS in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for TIMELESS antibody (AA 72-1050) (ABIN7876618)

Target: TIMELESS (Timeless Homolog (TIMELESS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMELESS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TIMELESS Antibody

Binding Specificity: AA 72-1050

Purpose: TIMELESS Antibody / TIM1 / TIM

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q72-E1050) was used as the immunogen for the TIMELESS antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TIMELESS antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TIMELESS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TIMELESS

Target: TIMELESS (Timeless Homolog (TIMELESS))

Alternative Name: TIMELESS

Background: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.

UniProt: Q9UNS1

Pathways: Protein targeting to Nucleus, Photoperiodism