AARS2 antibody (AA 729-968)

Catalog No. ABIN7876648

The Rabbit Polyclonal anti-AARS2 antibody (ABIN7876648) specifically detects AARS2 in WB, ELISA, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for AARS2 antibody (AA 729-968) (ABIN7876648)

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AARS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-AARS2 Antibody

Binding Specificity: AA 729-968

Purpose: AlaRS Antibody / Alanyl-tRNA synthetase / AARS1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R729-N968) was used as the immunogen for the AlaRS antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the AlaRS antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the AlaRS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for AARS2

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Alternative Name: AlaRS

Background: An aminoacyl-tRNA synthetase (AlaRS, aaRS or ARS), also called tRNA-ligase, is an enzyme that attaches the appropriate amino acid onto its corresponding tRNA. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

UniProt: P49588