INHA
Reactivity: Human
WB, IHC, ICC, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the Inhibin alpha antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
4 °C,-20 °C
Storage Comment
Store the Inhibin alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
Inhibin alpha (INHA)
(Inhibin, alpha (INHA))
Alternative Name
Inhibin alpha / INHA
Background
It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.