CD51 antibody (AA 732-970)

Catalog No. ABIN7876694

This Mouse Monoclonal antibody specifically detects CD51 in WB, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD51 antibody (AA 732-970) (ABIN7876694)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD51 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8B10H2

Product Details anti-CD51 Antibody

Binding Specificity: AA 732-970

Purpose: CD51 Antibody / Integrin alpha V / ITGAV / Vitronectin Receptor

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids H732-D970) was used as the immunogen for the CD51 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the CD51 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CD51 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Alternative Name: CD51

Background: Integrin alpha-V / CD51 is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily(cytoadhesins). The human locus for the av gene (VNRA) was previously mapped to the long arm of chromosome 2. Sims et al.(2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex