PON2 antibody (AA 74-101)

Catalog No. ABIN7876700

This Rabbit Polyclonal antibody specifically detects PON2 in WB, IF and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for PON2 antibody (AA 74-101) (ABIN7876700)

Target: PON2 (Paraoxonase 2 (PON2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PON2 Antibody

Binding Specificity: AA 74-101

Purpose: Paraoxonase 2 Antibody / PON2

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 74-101 from the human protein was used as the immunogen for the Paraoxonase 2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Paraoxonase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Paraoxonase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PON2

Target: PON2 (Paraoxonase 2 (PON2))

Alternative Name: Paraoxonase 2

Background: PON2 is a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes.

UniProt: Q15165