NDE1 antibody (AA 74-335)

Catalog No. ABIN7876714

The Rabbit Polyclonal anti-NDE1 antibody (ABIN7876714) specifically detects NDE1 in WB, ELISA, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for NDE1 antibody (AA 74-335) (ABIN7876714)

Target: NDE1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-NDE1 Antibody

Binding Specificity: AA 74-335

Purpose: NDE1 Antibody / NudE

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids E74-C335) was used as the immunogen for the NDE1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NDE1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NDE1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NDE1

Target: NDE1

Alternative Name: NDE1

Background: Nuclear distribution protein nudE homolog 1 is a protein that in humans is encoded by the NDE1 gene. This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants.

UniProt: Q9NXR1