PLA2G3 antibody (AA 74-358)

Catalog No. ABIN7876715

This Rabbit Polyclonal antibody specifically detects PLA2G3 in WB, ELISA and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for PLA2G3 antibody (AA 74-358) (ABIN7876715)

Target: PLA2G3 (Phospholipase A2, Group III (PLA2G3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PLA2G3 Antibody

Binding Specificity: AA 74-358

Purpose: PLA2G3 Antibody

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids E74-R358) was used as the immunogen for the PLA2G3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PLA2G3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PLA2G3 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PLA2G3

Target: PLA2G3 (Phospholipase A2, Group III (PLA2G3))

Alternative Name: PLA2G3

Background: This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease.

UniProt: Q9NZ20