GLN1 antibody (AA 74-371)

Catalog No. ABIN7876716

The Rabbit Polyclonal anti-GLN1 antibody is suitable to detect GLN1 in samples from Zebrafish (Danio rerio). It has been validated for WB and IHC (p).

Quick Overview for GLN1 antibody (AA 74-371) (ABIN7876716)

Target: GLN1 (Glutamine Synthetase (GLN1))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GLN1 Antibody

Binding Specificity: AA 74-371

Purpose: Zebrafish Glutamine synthetase Antibody / Glula / Glulb

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Glula/b recombinant protein (amino acids N74-Y371) was used as the immunogen for the Zebrafish Glutamine synthetase antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Glutamine synthetase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Glutamine synthetase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GLN1

Target: GLN1 (Glutamine Synthetase (GLN1))

Alternative Name: Glutamine synthetase

Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

UniProt: Q7T2P7

Pathways: Positive Regulation of Peptide Hormone Secretion