SYCP3 antibody (AA 75-236)

Catalog No. ABIN7876729

The Rabbit Polyclonal anti-SYCP3 antibody (ABIN7876729) specifically detects SYCP3 in WB, ELISA, FACS, IF and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SYCP3 antibody (AA 75-236) (ABIN7876729)

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYCP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SYCP3 Antibody

Binding Specificity: AA 75-236

Purpose: Synaptonemal Complex Protein 3 Antibody / SYCP3

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E75-F236) was used as the immunogen for the Synaptonemal Complex Protein 3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Synaptonemal Complex Protein 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Synaptonemal Complex Protein 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SYCP3

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Alternative Name: Synaptonemal Complex Protein 3

Background: SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.

UniProt: Q8IZU3