Neurexin 1 antibody (AA 77-110)

Catalog No. ABIN7876757

This Rabbit Polyclonal antibody specifically detects Neurexin 1 in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Neurexin 1 antibody (AA 77-110) (ABIN7876757)

Target: Neurexin 1 (NRXN1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurexin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Neurexin 1 Antibody

Binding Specificity: AA 77-110

Purpose: NRXN1 Antibody / Neurexin 1 beta

Purification: Antigen affinity

Immunogen: A portion of amino acids 77-110 from the human protein was used as the immunogen for this NRXN1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the NRXN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the NRXN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Neurexin 1

Target: Neurexin 1 (NRXN1)

Alternative Name: NRXN1

Background: Neurexin 1 is primarily known for its role in the formation and maintenance of synapses, the connections between neurons that allow for communication in the brain. It acts as a cell adhesion molecule, helping to guide the development of synapses and ensuring proper signaling between neurons. Studies have shown that mutations in the NRXN1 gene can lead to disruptions in synaptic function, ultimately impacting brain development and function. These mutations have been associated with a variety of neurological disorders, including autism spectrum disorder, schizophrenia, and intellectual disabilities.

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development