SCML1 antibody (AA 8-322)

Catalog No. ABIN7876819

The Rabbit Polyclonal anti-SCML1 antibody (ABIN7876819) specifically detects SCML1 in WB, ELISA, IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for SCML1 antibody (AA 8-322) (ABIN7876819)

Target: SCML1 (Sex Comb On Midleg-Like 1 (SCML1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCML1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-SCML1 Antibody

Binding Specificity: AA 8-322

Purpose: SCML1 Antibody / Sex comb on midleg-like protein 1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E8-K322) was used as the immunogen for the SCML1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SCML1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SCML1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SCML1

Target: SCML1 (Sex Comb On Midleg-Like 1 (SCML1))

Alternative Name: SCML1

Background: Putative Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. SCML1 (sex comb on midleg-like 1 (Drosophila)), is a 329 amino acid PcG protein belonging to the SCM family. Localizing to nucleus, SCML1 plays a role in testis development, spermatogenesis and embryonal development. While ubiquitously expressed, SCML1 is found at highest levels in adult skeletal muscle, heart and fetal liver. SCML1 contains one SAM (sterile alpha motif) domain and is encoded by a gene that spans 18 kb, contains 6 exons, maps to human chromosome Xp22.13, and is transcribed from telomere to centromere. Three SCML1 isoforms exist as a result of alternative splicing events.

UniProt: Q9UN30