SORD antibody (AA 8-357)

Catalog No. ABIN7876827

The Rabbit Polyclonal anti-SORD antibody is suitable to detect SORD in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, FACS and IHC (p).

Quick Overview for SORD antibody (AA 8-357) (ABIN7876827)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SORD Antibody

Binding Specificity: AA 8-357

Purpose: SORD Antibody / Sorbitol Dehydrogenase

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids N8-P357) was used as the immunogen for the SORD antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SORD antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SORD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD

Background: Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene. Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

UniProt: Q00796