SIGLEC5 antibody (AA 8-39)

Catalog No. ABIN7876834

The Rabbit Polyclonal anti-SIGLEC5 antibody (ABIN7876834) specifically detects SIGLEC5 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SIGLEC5 antibody (AA 8-39) (ABIN7876834)

Target: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGLEC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SIGLEC5 Antibody

Binding Specificity: AA 8-39

Purpose: SIGLEC5 Antibody

Purification: Purified

Immunogen: A portion of amino acids 8-39 from the human protein was used as the immunogen for the SIGLEC5 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the SIGLEC5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SIGLEC5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SIGLEC5

Target: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Alternative Name: SIGLEC5

Background: SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differenciation.

UniProt: O15389