FLCN antibody (AA 8-551)

Catalog No. ABIN7876838

This Rabbit Polyclonal antibody specifically detects FLCN in WB, ELISA, IF, FACS and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FLCN antibody (AA 8-551) (ABIN7876838)

Target: FLCN (Folliculin (FLCN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLCN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FLCN Antibody

Binding Specificity: AA 8-551

Purpose: Folliculin Antibody / FLCN

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids C8-K551) was used as the immunogen for the Folliculin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Folliculin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Folliculin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FLCN

Target: FLCN (Folliculin (FLCN))

Alternative Name: Folliculin

Target Type: Amino Acid

Background: Folliculin also known as FLCN, Birt-Hogg-Dube syndrome protein or FLCN_HUMAN is a protein that in humans is associated with Birt-Hogg-Dube syndrome and hereditary spontaneous pneumothorax. It is encoded by the Folliculin (FLCN) gene (alias BHD, FLCL) that acts as a tumor suppressor gene. It is mapped to 17p11.2. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization