HSD17B13 antibody (AA 81-110)

Catalog No. ABIN7876884

The Rabbit Polyclonal anti-HSD17B13 antibody is suitable to detect HSD17B13 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for HSD17B13 antibody (AA 81-110) (ABIN7876884)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HSD17B13 Antibody

Binding Specificity: AA 81-110

Purpose: HSD17B13 Antibody / DHB13 / 7-beta hydroxysteroid dehydrogenase 13

Purification: Antigen affinity

Immunogen: A portion of amino acids 81-110 from the human protein was used as the immunogen for this HSD17B13 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the HSD17B13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HSD17B13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Alternative Name: HSD17B13

Background: HSD17B13 protein is an enzyme that plays a key role in the metabolism of steroids and lipids in the body. Specifically, it is involved in the conversion of various hormones and fatty acids, making it a critical player in maintaining metabolic homeostasis. Additionally, studies have shown that mutations or dysregulation of the HSD17B13 gene can lead to impaired lipid metabolism and contribute to the development of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease. HSD17B13 protein is a potential therapeutic target for liver diseases.

UniProt: Q7Z5P4