IARS antibody (AA 812-1056)

Catalog No. ABIN7876903

The Rabbit Polyclonal anti-IARS antibody (ABIN7876903) specifically detects IARS in WB, ELISA, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for IARS antibody (AA 812-1056) (ABIN7876903)

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IARS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-IARS Antibody

Binding Specificity: AA 812-1056

Purpose: IARS1 Antibody / Isoleucine--tRNA ligase, cytoplasmic

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids E812-E1056) was used as the immunogen for the IARS1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IARS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IARS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IARS

Target: IARS (Isoleucyl-tRNA Synthetase (IARS))

Alternative Name: IARS1

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.

UniProt: P41252