PKD2 antibody (AA 829-893)

Catalog No. ABIN7876929

The Rabbit Polyclonal anti-PKD2 antibody is suitable to detect PKD2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC (p) and FACS.

Quick Overview for PKD2 antibody (AA 829-893) (ABIN7876929)

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-PKD2 Antibody

Binding Specificity: AA 829-893

Purpose: Polycystin 2 Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids S829-R893) was used as the immunogen for the Polycystin 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Polycystin 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Polycystin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PKD2

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Alternative Name: Polycystin 2

Background: Polycystin-2 is a protein that in humans is encoded by the PKD2 gene. It is mapped to 4q22.1. This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

UniProt: Q13563

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity