The Rabbit Polyclonal anti-Sorting Nexin 1 antibody is suitable to detect Sorting Nexin 1 in samples from Human. It has been validated for WB, ELISA, IF, IHC (p) and FACS.
SNX1
Reactivity: Rat
ELISA, IF (p), IHC (p), IF (cc), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the Sorting nexin 1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the Sorting nexin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
Sorting Nexin 1 (SNX1)
Alternative Name
Sorting nexin 1
Background
Sorting nexin-1 is a protein that in humans is encoded by the SNX1 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.