Nebulette antibody (AA 86-842)

Catalog No. ABIN7877004

The Rabbit Polyclonal anti-Nebulette antibody is suitable to detect Nebulette in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC (p).

Quick Overview for Nebulette antibody (AA 86-842) (ABIN7877004)

Target: Nebulette (NEBL)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nebulette antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Nebulette Antibody

Binding Specificity: AA 86-842

Purpose: Nebulette Antibody / NEBL

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E86-K842) was used as the immunogen for the Nebulette antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Nebulette antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Nebulette antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Nebulette

Target: Nebulette (NEBL)

Alternative Name: Nebulette

Background: Nebulette is a cardiac-specific isoform belonging to the nebulin family of proteins. It is encoded by the NEBL gene. This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.

UniProt: O76041