MVP antibody (AA 863-893)

Catalog No. ABIN7877005

The Rabbit Polyclonal anti-MVP antibody (ABIN7877005) specifically detects MVP in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for MVP antibody (AA 863-893) (ABIN7877005)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVP antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MVP Antibody

Binding Specificity: AA 863-893

Purpose: Major Vault Protein Antibody / MVP

Purification: Purified

Immunogen: A portion of amino acids 863-893 from the human protein was used as the immunogen for the Major Vault Protein antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Major Vault Protein antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Major Vault Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: Major Vault Protein

Background: MVP, the major vault protein, is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance.

UniProt: Q14764