ERLIN2 antibody (AA 87-339)

Catalog No. ABIN7877017

The Mouse Monoclonal anti-ERLIN2 antibody (Clone 3H9A2) (ABIN7877017) specifically detects ERLIN2 in WB, IF, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ERLIN2 antibody (AA 87-339) (ABIN7877017)

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERLIN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3H9A2

Product Details anti-ERLIN2 Antibody

Binding Specificity: AA 87-339

Purpose: ERLIN2 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D87-N339) was used as the immunogen for the ERLIN2 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the ERLIN2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ERLIN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ERLIN2

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Alternative Name: ERLIN2

Background: Erlin-2 is a protein that in humans is encoded by the ERLIN2 gene. This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: O94905