SERPINC1 antibody (AA 89-464)

Catalog No. ABIN7877059

The Rabbit Polyclonal anti-SERPINC1 antibody (ABIN7877059) specifically detects SERPINC1 in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SERPINC1 antibody (AA 89-464) (ABIN7877059)

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-SERPINC1 Antibody

Binding Specificity: AA 89-464

Purpose: SERPINC1 Antibody / Antithrombin III

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R89-K464) was used as the immunogen for the SERPINC1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SERPINC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SERPINC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Alternative Name: SERPINC1

Background: Serpin peptidase inhibitor, clade C (antithrombin), member 1, also known as Antithrombin III (AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

UniProt: P01008