Recombinant CTNND1 antibody (AA 900-1)

Catalog No. ABIN7877112

The Rabbit Monoclonal anti-CTNND1 antibody is suitable to detect CTNND1 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CTNND1 antibody (AA 900-1) (ABIN7877112)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CTNND1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CTNND1-4383R

Product Details anti-CTNND1 Antibody

Binding Specificity: AA 900-1

Purpose: Recombinant Delta 1 Catenin Antibody / CTNND1 / p120 Catenin (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 900-1,000 was used as the immunogen for the recombinant Delta 1 Catenin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant Delta 1 Catenin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant Delta 1 Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Alternative Name: Delta 1 Catenin

Background: Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.

UniProt: O60716

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling