FAF1 antibody (AA 91-650)

Catalog No. ABIN7877143

The Rabbit Polyclonal anti-FAF1 antibody (ABIN7877143) specifically detects FAF1 in WB, ELISA, FACS and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FAF1 antibody (AA 91-650) (ABIN7877143)

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-FAF1 Antibody

Binding Specificity: AA 91-650

Purpose: FAS-associated factor 1 Antibody / FAF1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R91-E650) was used as the immunogen for the FAS-associated factor 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FAS-associated factor 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the FAS-associated factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Alternative Name: FAS-associated factor 1

Background: Fas-associated factor-1 (FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location