GJB1 antibody (AA 92-147)

Catalog No. ABIN7877153

This Rabbit Polyclonal antibody specifically detects GJB1 in WB, FACS and ELISA. It exhibits reactivity toward Human.

Quick Overview for GJB1 antibody (AA 92-147) (ABIN7877153)

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Product Details anti-GJB1 Antibody

Binding Specificity: AA 92-147

Purpose: GJB1 Antibody / Gap junction beta-1 protein / Connexin 32

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids A92-A147) was used as the immunogen for the GJB1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GJB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GJB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GJB1

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Alternative Name: GJB1

Background: Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32) is a transmembrane protein that in humans is encoded by the GJB1 gene. This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

UniProt: P08034

Pathways: Cell-Cell Junction Organization