Claudin 7 antibody (AA 92-211)

Catalog No. ABIN7877154

The Rabbit Polyclonal anti-Claudin 7 antibody is suitable to detect Claudin 7 in samples from Human. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for Claudin 7 antibody (AA 92-211) (ABIN7877154)

Target: Claudin 7 (CLDN7)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-Claudin 7 Antibody

Binding Specificity: AA 92-211

Purpose: Claudin 7 Antibody

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids F92-V211) was used as the immunogen for the Claudin 7 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Claudin 7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Claudin 7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Claudin 7

Target: Claudin 7 (CLDN7)

Alternative Name: Claudin 7

Background: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.

UniProt: O95471

Pathways: Hepatitis C