nectin-3 antibody (AA 92-296)

Catalog No. ABIN7877170

The Rabbit Polyclonal anti-nectin-3 antibody (ABIN7877170) specifically detects nectin-3 in WB, ELISA, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for nectin-3 antibody (AA 92-296) (ABIN7877170)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This nectin-3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-nectin-3 Antibody

Binding Specificity: AA 92-296

Purpose: Nectin 3 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids E92-N296) was used as the immunogen for the Nectin 3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Nectin 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Nectin 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Alternative Name: Nectin 3

Background: Nectin-3, also known as poliovirus receptor-related 3, is a 95 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. It is mapped to 3q13.13. This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization