SLIT2 antibody (AA 934-1529)

Catalog No. ABIN7877187

The Rabbit Polyclonal anti-SLIT2 antibody is suitable to detect SLIT2 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for SLIT2 antibody (AA 934-1529) (ABIN7877187)

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLIT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-SLIT2 Antibody

Binding Specificity: AA 934-1529

Purpose: SLIT2 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids N934-S1529) was used as the immunogen for the SLIT2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SLIT2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SLIT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SLIT2

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Alternative Name: SLIT2

Background: Slit homolog 2 protein is a protein that in humans is encoded by the SLIT2 gene. This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants.

UniProt: O94813

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration