RNF4 antibody (AA 95-123)

Catalog No. ABIN7877212

The Rabbit Polyclonal anti-RNF4 antibody (ABIN7877212) specifically detects RNF4 in WB, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for RNF4 antibody (AA 95-123) (ABIN7877212)

Target: RNF4 (Ring Finger Protein 4 (RNF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-RNF4 Antibody

Binding Specificity: AA 95-123

Purpose: RNF4 Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 95-123 from the human protein was used as the immunogen for the RNF4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the RNF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the RNF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for RNF4

Target: RNF4 (Ring Finger Protein 4 (RNF4))

Alternative Name: RNF4

Background: The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.

UniProt: P78317

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway