Claudin 1 antibody (AA 96-211)

Catalog No. ABIN7877243

This Rabbit Polyclonal antibody specifically detects Claudin 1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Claudin 1 antibody (AA 96-211) (ABIN7877243)

Target: Claudin 1 (CLDN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Claudin 1 Antibody

Binding Specificity: AA 96-211

Purpose: CLDN1 Antibody / Claudin 1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids F96-V211) was used as the immunogen for the CLDN1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CLDN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CLDN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Claudin 1

Target: Claudin 1 (CLDN1)

Alternative Name: CLDN1

Background: Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C