ITGA3 antibody (AA 96-324)

Catalog No. ABIN7877250

The Rabbit Polyclonal anti-ITGA3 antibody is suitable to detect ITGA3 in samples from Human. It has been validated for WB, ELISA, FACS, IF and IHC (p).

Quick Overview for ITGA3 antibody (AA 96-324) (ABIN7877250)

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITGA3 Antibody

Binding Specificity: AA 96-324

Purpose: Integrin alpha 3 Antibody / ITGA3

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids L96-L324) was used as the immunogen for the Integrin alpha 3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Integrin alpha 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Integrin alpha 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ITGA3

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Alternative Name: Integrin alpha 3

Background: ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. This gene is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the ?3?1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex