Recombinant CNN1 antibody (C-Term)

Catalog No. ABIN7877327

This Rabbit Monoclonal antibody specifically detects CNN1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant CNN1 antibody (C-Term) (ABIN7877327)

Target: CNN1 (Calponin 1 (CNN1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CNN1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CNN1-4227R

Product Details anti-CNN1 Antibody

Binding Specificity: C-Term

Purpose: Recombinant CNN1 Antibody / Calponin-1

Purification: Protein A affinity chromatography

Immunogen: A synthetic peptide from the C-terminus of the human protein was used as the immunogen for the recombinant CNN1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant CNN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant CNN1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CNN1

Target: CNN1 (Calponin 1 (CNN1))

Alternative Name: CNN1

Background: Calponin-1/CNN1, a 33 kDa polypeptide, is a cytoskeleton-associated actin-binding protein that also interacts tropomyosin and calmodulin. Calponin antibody has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast. Calponin antibody may also have applications in malignant myoepithelium and pleomorphic adenoma of salivary gland as well as a useful marker for fine needle aspirates of papillary breast lesions. The antibody has been found in tissue extracts from smooth muscle, but not in fibroblast extracts.

UniProt: P51911