KRT16 antibody (C-Term)
Quick Overview for KRT16 antibody (C-Term) (ABIN7877413)
Target
See all KRT16 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
-
-
Binding Specificity
- C-Term
-
Purpose
- Cytokeratin 16 Antibody KRT16 (azide and preservative free)
-
Purification
- Protein G affinity chromatography
-
Immunogen
- An amino acid sequence from the C-terminal region of the protein was used as the immunogen for this Cytokeratin 16 antibody.
-
Isotype
- IgG1, kappa
-
-
-
-
Application Notes
- Optimal dilution of the Cytokeratin 16 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Preservative
- Azide free
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store the Cytokeratin 16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- KRT16 (Keratin 16 (KRT16))
-
Alternative Name
- Cytokeratin 16
-
Background
- Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.
-
UniProt
- P08779
Target
-