KRT16 antibody (C-Term)

Catalog No. ABIN7877414

This Mouse Monoclonal antibody specifically detects KRT16 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for KRT16 antibody (C-Term) (ABIN7877414)

Target: KRT16 (Keratin 16 (KRT16))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT16 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: LL025

Product Details anti-KRT16 Antibody

Binding Specificity: C-Term

Purpose: Cytokeratin 16 Antibody KRT16

Purification: Protein G affinity chromatography

Immunogen: An amino acid sequence from the C-terminal region of the protein was used as the immunogen for this Cytokeratin 16 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Cytokeratin 16 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Cytokeratin 16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for KRT16

Target: KRT16 (Keratin 16 (KRT16))

Alternative Name: Cytokeratin 16

Background: Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.

UniProt: P08779