PLAP antibody (C-Term)

Catalog No. ABIN7877456

This Mouse Monoclonal antibody specifically detects PLAP in WB, FACS, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PLAP antibody (C-Term) (ABIN7877456)

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLAP antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6C7G3

Product Details anti-PLAP Antibody

Binding Specificity: C-Term

Purpose: Placental Alkaline Phosphatase Antibody / ALPP / PLAP

Sequence: KARDRKAYTV LLYGNGPGYV LKDGARPDVT E

Purification: Antigen affinity purified

Immunogen: C-terminal amino acids KARDRKAYTVLLYGNGPGYVLKDGARPDVTE were used as the immunogen for the Placental Alkaline Phosphatase antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the Placental Alkaline Phosphatase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Placental Alkaline Phosphatase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PLAP

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Alternative Name: Placental Alkaline Phosphatase

Background: Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene. The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.

UniProt: P05187