S100A12 antibody (C-Term)

Catalog No. ABIN7877470

The Rabbit Polyclonal anti-S100A12 antibody (ABIN7877470) specifically detects S100A12 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for S100A12 antibody (C-Term) (ABIN7877470)

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A12 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-S100A12 Antibody

Binding Specificity: C-Term

Purpose: S100A12 Antibody

Purification: Antigen affinity chromatography

Immunogen: A synthetic peptide from the C-terminus of human S100A12 was used as the immunogen for the S100A12 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the S100A12 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the S100A12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for S100A12

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Alternative Name: S100A12

Background: S100 calcium-binding protein A12 (S100A12) is a protein that in humans is encoded by the S100A12 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

UniProt: P80511

Pathways: Toll-Like Receptors Cascades, S100 Proteins