Recombinant S100P antibody (C-Term)

Catalog No. ABIN7877472

The Rabbit Monoclonal anti-S100P antibody is suitable to detect S100P in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant S100P antibody (C-Term) (ABIN7877472)

Target: S100P (S100 Calcium Binding Protein P (S100P))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This S100P antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: S100P-4386R

Product Details anti-S100P Antibody

Binding Specificity: C-Term

Purpose: Recombinant S100P Antibody

Purification: Protein A affinity chromatography

Immunogen: A recombinant fragment corresponding to the C-terminal region of human S100P protein was used as the immunogen for the recombinant S100P antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant S100P antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant S100P antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for S100P

Target: S100P (S100 Calcium Binding Protein P (S100P))

Alternative Name: S100P

Background: S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

UniProt: P25815

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins