Trefoil Factor 2 antibody (C-Term)

Catalog No. ABIN7877489

This Mouse Monoclonal antibody specifically detects Trefoil Factor 2 in ELISA. It exhibits reactivity toward Human.

Quick Overview for Trefoil Factor 2 antibody (C-Term) (ABIN7877489)

Target: Trefoil Factor 2 (TFF2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Trefoil Factor 2 antibody is un-conjugated

Application: ELISA

Clone: GE16C

Product Details anti-Trefoil Factor 2 Antibody

Binding Specificity: C-Term

Purpose: TFF2 Antibody / Trefoil factor 2

Purification: PEG precipitation

Immunogen: A synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2 protein was used as the immunogen for this TFF2 antibody.

Isotype: IgM, kappa

Application Details

Application Notes: Optimal dilution of the TFF2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the TFF2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Trefoil Factor 2

Target: Trefoil Factor 2 (TFF2)

Alternative Name: TFF2

Background: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.

UniProt: Q03403