UFC1 antibody (C-Term)

Catalog No. ABIN7877493

The Rabbit Polyclonal anti-UFC1 antibody is suitable to detect UFC1 in samples from Human and Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for UFC1 antibody (C-Term) (ABIN7877493)

Target: UFC1 (Ubiquitin-Fold Modifier Conjugating Enzyme 1 (UFC1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UFC1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-UFC1 Antibody

Binding Specificity: C-Term

Purpose: Ufm1-conjugating enzyme 1 Antibody / Ufc1

Purification: Antigen affinity purified

Immunogen: An amino acid sequence from the C-terminal region of the human protein was used as the immunogen for the Ufm1-conjugating enzyme 1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Ufm1-conjugating enzyme 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles

Storage: -20 °C

Storage Comment: Aliquot the Ufm1-conjugating enzyme 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for UFC1

Target: UFC1 (Ubiquitin-Fold Modifier Conjugating Enzyme 1 (UFC1))

Alternative Name: Ufm1-conjugating enzyme 1

Background: Various ubiquitin-like (UBL) post-translational modifiers contribute critically to the protein degradation pathway . These UBLs are covalently linked to most target proteins through an enzymatic cascade analogous to ubiquitylation, consisting of E1 (activating), E2 (conjugating), and E3 (ligating) enzymes. Ufc1 Belongs to the ubiquitin-conjugating enzyme family, and is an E2-like enzyme which forms an intermediate with UFM1, a novel ubiquitin-fold modifier, via thioester linkage.

UniProt: Q9Y3C8