Recombinant VLDLR antibody (C-Term)

Catalog No. ABIN7877495

This Mouse Monoclonal antibody specifically detects VLDLR in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant VLDLR antibody (C-Term) (ABIN7877495)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VLDLR antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RVLDLR-1337

Product Details anti-VLDLR Antibody

Binding Specificity: C-Term

Purpose: VLDLR Antibody / VLDL Receptor

Purification: Protein A/G affinity

Immunogen: A recombinant human protein fragment from the C-terminal region was used as the immunogen for the VLDLR antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the VLDLR antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the VLDLR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Alternative Name: VLDLR

Background: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin