Recombinant VLDLR antibody (C-Term)

Catalog No. ABIN7877496

The Rabbit Monoclonal anti-VLDLR antibody is suitable to detect VLDLR in samples from Human. It has been validated for ELISA.

Quick Overview for Recombinant VLDLR antibody (C-Term) (ABIN7877496)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This VLDLR antibody is un-conjugated

Application: ELISA

Grade: Carrier-free

Clone: VLDLR-2896R

Product Details anti-VLDLR Antibody

Binding Specificity: C-Term

Purpose: Recombinant VLDL Receptor Antibody / VLDLR (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the C-terminal region of VLDLR was used as the immunogen for this recombinant VLDL Receptor antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant VLDL Receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant VLDL Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Alternative Name: VLDL Receptor

Background: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin