IL-10RA antibody (Extracellular)

Catalog No. ABIN7877549

This Rat Monoclonal antibody specifically detects IL-10RA in FACS. It exhibits reactivity toward Mouse.

Quick Overview for IL-10RA antibody (Extracellular) (ABIN7877549)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10RA antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: Carrier-free

Clone: 1B1-3a

Product Details anti-IL-10RA Antibody

Binding Specificity: Extracellular

Purpose: IL-10RA Antibody / IL-10R1 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the IL-10RA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the IL-10RA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Alternative Name: IL-10RA

Background: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

UniProt: Q61727

Pathways: Growth Factor Binding