IL-10RA antibody (Extracellular)

Catalog No. ABIN7877550

The Rat Monoclonal anti-IL-10RA antibody is suitable to detect IL-10RA in samples from Mouse. It has been validated for FACS.

Quick Overview for IL-10RA antibody (Extracellular) (ABIN7877550)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10RA antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 1B1-3a

Product Details anti-IL-10RA Antibody

Binding Specificity: Extracellular

Purpose: IL-10RA Antibody / IL-10R1

Purification: Protein G affinity chromatography

Immunogen: Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the IL-10RA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the IL-10RA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Alternative Name: IL-10RA

Background: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

UniProt: Q61727

Pathways: Growth Factor Binding