BCL2L2 antibody (full length)

Catalog No. ABIN7877719

The Mouse Monoclonal anti-BCL2L2 antibody (Clone PCRP-BCL2L2-1A4) (ABIN7877719) specifically detects BCL2L2 in IF and FACS. The antibody is reactive with Human samples.

Quick Overview for BCL2L2 antibody (full length) (ABIN7877719)

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-BCL2L2-1A4

Product Details anti-BCL2L2 Antibody

Binding Specificity: full length

Purpose: Bcl-W Antibody / Bcl2L2

Purification: Protein A/G affinity

Immunogen: Recombinant human full-length BCL2L2/Bcl-W protein was used as the immunogen for the Bcl-W antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the Bcl-W antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Bcl-W antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: Bcl-W

Background: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

UniProt: Q92843