Recombinant Cadherin-16 antibody (full length)

Catalog No. ABIN7877746

The Rabbit Monoclonal anti-Cadherin-16 antibody (Clone CDH16-7028R) (ABIN7877746) specifically detects Cadherin-16 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Cadherin-16 antibody (full length) (ABIN7877746)

Target: Cadherin-16 (CDH16)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDH16-7028R

Product Details anti-Cadherin-16 Antibody

Binding Specificity: full length

Purpose: Recombinant CDH16 Antibody / Cadherin 16

Purification: Protein A affinity

Immunogen: Recombinant human full-length protein was used as the immunogen for the recombinant CDH16 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant CDH16 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant CDH16 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: CDH16

Background: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin/cadherin 16/CDH16. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

UniProt: O75309