Recombinant Cadherin-16 antibody (full length)
Quick Overview for Recombinant Cadherin-16 antibody (full length) (ABIN7877749)
Target
See all Cadherin-16 (CDH16) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Binding Specificity
- full length
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Purpose
- Recombinant Ksp-Cadherin Antibody / Cadherin 16 (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogen
- Recombinant human full-length CDH16 protein was used as the immunogen for the recombinant Ksp-Cadherin antibody.
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Isotype
- IgG1, kappa
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Application Notes
- Optimal dilution of the recombinant Ksp-Cadherin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- -20 °C
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Storage Comment
- Aliquot the recombinant Ksp-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cadherin-16 (CDH16)
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Alternative Name
- Ksp-Cadherin
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Background
- This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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UniProt
- O75309
Target
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