CREB5 antibody (full length)

Catalog No. ABIN7877764

The Mouse Monoclonal anti-CREB5 antibody (Clone PCRP-CREB5-1G8) (ABIN7877764) specifically detects CREB5 in WB, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for CREB5 antibody (full length) (ABIN7877764)

Target: CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CREB5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-CREB5-1G8

Product Details anti-CREB5 Antibody

Binding Specificity: full length

Purpose: CREB5 Antibody / CRE-BPa

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human CREB5 protein was used as the immunogen for the CREB5 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the CREB5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CREB5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CREB5

Target: CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))

Alternative Name: CREB5

Background: The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.

UniProt: Q02930

Pathways: Thyroid Hormone Synthesis